Preheat the air fryer to 375°F (190°C) for about 3 minutes. A hot basket helps the bread begin crisping as soon as the roll-ups are added.

Trim the crusts from all eight bread slices, then flatten each slice thoroughly with a rolling pin. Flattening makes the bread flexible enough to wrap tightly around the filling without splitting.

Spread approximately 1 teaspoon of pizza sauce over each flattened slice, leaving a small border around the edges. Add 3–4 pepperoni slices and place one mozzarella stick in the center, or use about 2 tablespoons of shredded low-moisture mozzarella.

Roll each slice tightly around its filling, then finish with the seam underneath. Keeping the seam at the bottom helps the roll-up stay closed during cooking.

Stir together the melted butter, grated Parmesan, and Italian seasoning. Brush the mixture lightly over each roll-up so the bread browns without becoming greasy.

Arrange the roll-ups seam-side down in a single layer in the air-fryer basket, leaving space between them for air circulation. Air-fry at 375°F for 5–7 minutes, turning once if needed, until golden brown and crisp.

Serve the pizza roll-ups immediately while the cheese is hot and stretchy. Offer warm marinara or extra pizza sauce on the side for dipping.